Process for 3-(2-(7-chloro-2-quinolinyl)ethenyl) - benzaldehyde

摘要

The yield of monoaldehyde ##STR1## from 7-chloroquinaldine and isophthalaldehyde is increased to about 82% by using a 2 molar excess of isophthalaldehyde, conditions favoring precipitation of product during the reaction and recycling unreacted isophthalaldehyde. The recycling leads to a reduced net consumption of about 1.2 molar equivalents of isophthalaldehyde.