Process for producing amp;egr;-poly-L-lysine with immobilized Streptomyces albulus

摘要

An effective process for producing &egr;-poly-L-lysine is provided, which process comprises cultivating a microorganism having . epsilon.- poly-L-lysine productivity, such as a bacterium belonging to the Streptomyces genus, in the form of immobilized bacterial cells under aerobic conditions, and according to which process, the bacterial cells cause no bacteriolysis; the immobilized bacterial cells retaining . epsilon.-poly-L-lysine productivity can be easily separated and recovered from the culture solution containing &egr;-poly-L-lysine; and semi- continuous or continuous production of &egr;-poly-L-lysine by the use of the immobilized bacterial cells is possible.