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Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use

机译:具有抗胃泌素活性的芳香酸二酰胺,其制备方法及其药物用途

摘要

A compound represented by the general formula (I) shown below ##STR1## or a pharmaceutically acceptable salt thereof can be used as the active ingredient in a pharmaceutical preparation. The pharmaceutical preparation is desirable for its anti-ulcer activity, for therapeutic use against tumors sustained by gastrin and other bioactive polypeptides correlated therewith, for therapeutic use in treating disorders of the gastrointestinal tract, for the treatment of pathological conditions of the central nervous system linked to imbalances in the neural physiological levels of gastrin or other bioactive polypeptides correlated therewith, for use in the treatment and prevention of pathological eye conditions caused by surgical treatment of cataracts or chronic ocular inflammation, and for the prevention of diseases of other sensory organs.
机译:下述通式(I)所示的化合物或其药学上可接受的盐可以用作药物制剂中的活性成分。该药物制剂因其抗溃疡活性,针对由胃泌素和与其相关的其他生物活性多肽维持的肿瘤的治疗用途,用于治疗胃肠道疾病的治疗用途,用于治疗所联系的中枢神经系统病理状况而理想的药物胃泌素或与其相关的其他生物活性多肽的神经生理水平失调,用于治疗和预防由白内障或慢性眼部炎症的外科治疗引起的病理性眼部疾病,以及用于预防其他感觉器官的疾病。

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