System and method for enrichment of rare cell population from whole blood samples

摘要

A method for enriching rare cell populations from a whole blood sample by separating rare cell fractions from whole blood sample according to the relative charge density and/or the relative binding affinity for a leukocyte depletion solid phase matrix is described. The enrichment method may be operated stand alone, or as a pre or post- processing step in conjunction with a charge-flow separation method.