Unit medicine formulation for local hormone medical therapy of vagina drying

摘要

(57) Abstract The medicine formulation in order locally and essentially to deal with vagina drying and vagina drying of the especially menopause lady not to be systemic. The separation natural estrogen where as for this medicine also many of 17 esutorajioru 15g, have the estrogen content which is suitable to the equivalent unit dosage below 10g desirably, in the solution in the lipophilic medicine or the form of the suspended material are chosen from 17 esutorajioru and that salt, to especially particulates it was converted or to vector it contains with the gelatinizer and the moisture powder for the natural estrogen and the hydrophilic gel formation living body adhesive and the said lipophilic medicine which are converted. This medicine, takes the configuration of the soft capsule in one, this outside containing the gelatin and the glycerine, the hard or soft solid-state envelope and includes with the liquid or semi- liquid inner phase which contains the gelatinizer of the lipophilic medicine, the living body adhesive and the lipophilic medicine to which include the estrogen the solution or the suspended material in the form. In addition, with configuration of the sustained-release small ovate medicine, as for this the gelatinizer and the moisture powder of the lipophilic medicine, the hydrophilic gel formation living body adhesive and the lipophilic medicine which contain the estrogen in the form of the solution or the suspended material are contained, non-aqueous high solid or semi- soft solid-state homogeneous phase is included.