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Newly known platelet aggregation inhibitors
Newly known platelet aggregation inhibitors
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机译:最新已知的血小板凝集抑制剂
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摘要
Novel peptide mimetic compounds are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the chemical structure CHEM wherein x = 4 to 8, y = 0 to 4, W = CH2-CH2 or CH=CH, Z = H, COOH, CONH2, CH2OH, CO2R, CH2OR or C1-6 alkyl, R = C1-6 alkyl, Ar = a nitrogen-containing heterocyclic group other than pyridyl, and Asp = aspartic acid residue. re p
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机译:提供了新颖的肽模拟化合物,其具有作为血小板聚集抑制剂的有用活性。这些化合物的化学结构为,其中x = 4至8,y = 0至4,W = CH2-CH2或CH = CH,Z = H,COOH,CONH2,CH2OH,CO2R,CH2OR或C1-6烷基,R = C 1-6烷基,Ar =吡啶基以外的含氮杂环基,Asp =天冬氨酸残基。 p
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