SPIRO(TETRAHYDROPYRROLO1,2-A/PYRAZINE-4,3'-PYRROLIDINE) DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION THEREOF

摘要

The present invention relates to compounds of formula (I), to pharmaceutical compositions containing them, and to processes for their preparation. In the formula (I), R1 and R2 are independently hydrogen or halogen, trifluoromethyl, C1-6alkyl, C1-6alkoxy or nitro, and R3 is hydrogen or halogen. The compounds and their salts have aldose reductase inhibitory activity and are thus useful in the prevention and treatment of diabetic complications. ŕ