CHELATOR INCORPORATED ARG-GLY-ASP (RGD) MIMETIC SYNTHETIC DISINTEGRINS AS IMAGING AGENTS

摘要

The present invention describes novel compounds of formula (I) wherein R1, R2,R3, R4, and n are as defined herein, which act as antagonists of the plateletglycoprotein IIb/IIIa complex, 99mTc labeled radiopharmaceuticals madetherefrom, methods of using the same as imaging agents for the diagnosis ofarterial and venous thrombi, and kits comprising the same.