CHELATOR INCORPORATED ARG-GLY-ASP (RGD) MIMETIC SYNTHETIC DISINTEGRINS AS IMAGING AGENTS

摘要

The present invention describes novel compounds of formula (I) wherein R?1, R2, R3, R4¿, and n are as defined herein, which act as antagonists of the platelet glycoprotein IIb/IIIa complex, 99mTc labeled radiopharmaceuticals made therefrom, methods of using the same as imaging agents for the diagnosis of arterial and venous thrombi, and kits comprising the same.