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CYTOKINE REGULATORY AGENTS AND USE IN PATHOLOGIES AND CONDITIONS ASSOCIATED WITH ALTERED CYTOKINE LEVELS

机译:细胞因子调节剂及其在细胞因子水平改变的病态和状况中的使用

摘要

The present invention relates to novel peptides that are potent cytokine modulators. The invention also relates to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and cytokine modulator. Administration of the cytokine modulator to a subject to be administered may increase or inhibit cytokine activity. Accordingly, the present invention provides a method of modulating cytokine activity in a subject having a disease characterized by abnormalities or alterations in cytokine activity. In addition, the present invention also has adverse side effects caused by, for example, inactivity deconditioning, nitric oxide or cytokine mediated diseases, adverse drug reactions, obesity, sepsis shock, and cancer chemotherapy or as a response to organ transplantation. It provides a method of treating a disease comprising a.
机译:本发明涉及作为有效的细胞因子调节剂的新型肽。本发明还涉及包含药学上可接受的载体和细胞因子调节剂的药物组合物。向待施用的受试者施用细胞因子调节剂可增加或抑制细胞因子活性。因此,本发明提供了一种在患有以细胞因子活性异常或改变为特征的疾病的受试者中调节细胞因子活性的方法。另外,本发明还具有由例如不活动性减退,一氧化氮或细胞因子介导的疾病,不良药物反应,肥胖症,败血症休克和癌症化学疗法或作为对器官移植的反应所引起的不良副作用。它提供了一种治疗疾病的方法,包括

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