Electronic network, including the DNA and microelectronic components

摘要

An electronic network having a geometry defined by at least one fibre comprising one or more nucleotide chains (I) is new. Also new are: (1) electronic circuit containing such a network; (2) junction between two or more wires in which the end of each wire next to the junction comprises a (I) bound to another chain in the junction; (3) junction between a conductor (a fibre with one or more (I)) and an electrically conducting interface component; (4) junction similar to (3) between some component of an electronic circuit and an interface component in which (I) is attached to one component and bound, by biomolecular interaction, with a linker attached to the other component; (5) any component of the new network; (6) wire comprising a (I) fibre chemically or physically modified by binding to it an electrically conducting substance (A) so that a current can flow along the fibre; (7) field effect transistor (FET) consisting of this wire and serving as a gate; and (8) kits and reagents for making the network, junctions or components. (I) can include chemically modified nucleotides, allowing binding between fibres or binding to a linker or other component. Especially, the modification includes introduction of a specific binding component, e.g. of the biotin-(strept)avidin, sugar-lectin, etc., pairs. In the junction of (2), binding is by SSI, e.g. using a nucleic acid binding protein or specific binding pair as above, and (I) is modified covalently, e.g. via peptide or disulphide bond, or non-covalently. Suitable (A) include silver, gold, cobalt, etc., or a cluster or particle of metal or semiconductor.