首页> 外国专利> METHOD FOR DETECTING APOTOSIS-ACCELERATING GENE IN CELL AND MEDICINAL AGENT COMPRISING APOTOSIS-ACCELERATING GENE

METHOD FOR DETECTING APOTOSIS-ACCELERATING GENE IN CELL AND MEDICINAL AGENT COMPRISING APOTOSIS-ACCELERATING GENE

机译:检测细胞中凋亡促进基因的方法及包含凋亡促进基因的药物

摘要

PROBLEM TO BE SOLVED: To detect an apotosis-accelerating gene such as ARL1 in abnormal cells causing for diseases such as cancers relating to genes corresponding to a complex system such as a human, mammal and the like, provide the gene as a medicinal agent and enable to carry out a novel gene therapy. SOLUTION: This method for detecting apotosis-accelerating gene in cells is to contrast a normal cell having apotosis-accelerating gene with an abnormal cell defected in the apotosis-accelerating gene obtained by mutation in a gene region and specifically detect the apotosis-accelerating gene in the region. The apotosis-accelerating gene which accelerates apotosis in abnormal cells such as cancers is incorporated in a predetermined expression vector to obtain this medicinal agent.
机译:解决的问题:为了在引起与诸如人类,哺乳动物等复杂系统的基因相关的癌症等疾病的异常细胞中检测促进ATL1等凋亡的基因,提供该​​基因作为药物并使进行新的基因疗法成为可能。解决方案:这种检测细胞中促进细胞凋亡的基因的方法是将具有促进细胞凋亡的基因的正常细胞与通过基因区域突变获得的促进细胞凋亡的基因缺陷的异常细胞进行对比,并具体检测其中的促进细胞凋亡的基因。该区域。在预定的表达载体中掺入促进在癌症等异常细胞中促进细胞凋亡的促进细胞凋亡的基因,从而获得该药物。

著录项

  • 公开/公告号JP2001161362A

    专利类型

  • 公开/公告日2001-06-19

    原文格式PDF

  • 申请/专利权人 SHOOWA KK;

    申请/专利号JP19990346399

  • 发明设计人 ABUDOUPURU ABUDOKIRIMU;

    申请日1999-12-06

  • 分类号C12N15/09;A61K35/76;A61K48/00;A61P35/00;C12Q1/68;

  • 国家 JP

  • 入库时间 2022-08-22 01:32:49

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