A compound derived from naftalen - 5 - 1 - il - 1,3 Dioxane in the form of Pure stereoisomer or mixture of stereoisomers, Said medicine is made up,And Pharmaceutical composition containing Said Compound

摘要

1. Compounds in the form of stereoisomers or mixtures of stereoisomers, conforming to the general formula (IA),R1 represents an atom dehydrogeno or a c2-4 linear or branched tar, C3-6 cyclopropyl, C3-6 cyclopropyl or a tar in which phenyl c1-3 may be substituted in a phenyl nuclide; R2 represents a hydrogen atom or a C1-4 linear or branched tar, C3-6 cyclopropyl, C3-6 cycloquilmytio o fenil c1-3 coquilo eventualementesubistuido en el nucleo fenilo; R3 represents a water Xi or C1-4 alcox group or a nr4r5 universal formula group, wherein R4 and R5 respectively represent a hydrogen atom and a C1-4 linear synthetic tar group, A group of c-3-6 cyclopropyl or ungrupo C3-6 cyclopropyl ethyl ester,In a general formula (IB), R represents a hydrogen atom, or a general ch2coy formula group. In this formula group, R represents a hydrogen Xi group, a C1-4 alcoxi group, or a general ch2con1r2 formula group, wherein R1 and R2 are independent of each other, They represent a hydrogen atom or a C1-4 tar group; X represents an oxygen or sulfur atom or a CH2 group; m represents 0 or 1; n represents 0, 1 or 2, in the state of free radicals or acid-induced salts; R1 represents a hydrogen atom or a common preparation group in the total formula. C H2COY,In this case, it also represents a C1-4 alcoxi or ungrupo C1-4 alcoxi group, or a ch2conr4r5 total formula group, wherein R4 and R5 respectively represent an atomic dehidrogeno or C1-4 hydrocarbon group; R2 repeat establishes a piridin-2-ilo group, a piridin-3-ilo group, and a piridin-4-ilo group, A group of 1-methylpyridine-2-ilo, 1