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single compound or stereoisomers, mixtures of stereoisomers, or pharmaceutically acceptable salts thereof, pharmaceutical composition, and use of a compound or a pharmaceutically acceptable salt thereof

机译:单一化合物或立体异构体,立体异构体的混合物或其药学上可接受的盐,药物组合物以及化合物或其药学上可接受的盐的用途

摘要

"SINGLE COMPOUND OR STEREO, STEREO MIXTURES, OR PHARMACEUTICALLY ACCEPTABLE SALTS OF THE SAME, AND USE OF A COMPOUND OR PHARMACEUTICALLY ACCEPTED SALT OF THE SAME WITHOUT RISK. 1 ^ to R ^ 10 ^ are as described in the report, and at least one of CR ^ 5 ^ R ^ 6 ^ or CR ^ 7 ^ R ^ 8 ^ or CR ^ 9 ^ R ^ 10 ^ is an optionally substituted azetidine ring or an optionally substituted oxetane ring which may be useful in the manufacture of pharmaceutical compositions for treating lipoxygenase-mediated disorders They may also be useful in the manufacture of pharmaceutical formulations for treatment of lipoxygenase-mediated disorders.
机译:“该化合物的单一化合物或立体,混合物或药学可接受的盐,以及使用该化合物的化合物或药学可接受的盐而无风险。1 ^至R ^ 10 ^如本报告所述,并且至少有一个CR ^ 5 ^ R ^ 6 ^或CR ^ 7 ^ R ^ 8 ^或CR ^ 9 ^ R ^ 10 ^中的一个是任选取代的氮杂环丁烷环或任选取代的氧杂环丁烷环,可用于制备用于治疗脂氧合酶介导的疾病。它们还可用于制备用于治疗脂氧合酶介导的疾病的药物制剂。

著录项

  • 公开/公告号BRPI0520097A2

    专利类型

  • 公开/公告日2009-08-25

    原文格式PDF

  • 申请/专利权人 ELI LILLY AND COMPANY;

    申请/专利号BR2005PI20097

  • 申请日2005-12-09

  • 分类号C07D305/14;C07D493/10;

  • 国家 BR

  • 入库时间 2022-08-21 19:28:31

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