Composition, pharmaceutical formulation, combination and use related to the treatment of autoimmune diseases using antigen or tolerant agent in combination with methotrexate

摘要

"COMPOSITION, PHARMACEUTICAL FORMULATION, COMBINATION AND USE RELATED TO THE TREATMENT OF AUTOIMMUNE DISEASES USING ANTIGEN OR TOLERANT AGENT IN COMBINATION WITH METOTREXATE". A combination of a standard mucosally administrable antigen and an oral, enteric or parenterally administered methotrexate is employed to produce a pharmaceutical formulation and to treat or prevent autoimmune disease. The amounts of standard antigen and methotrexate are effective, in combination, to suppress the autoimmune response associated with autoimmune disease.