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Viral vectors having chimeric envelope proteins containing the igg-binding domain of protein a
Viral vectors having chimeric envelope proteins containing the igg-binding domain of protein a
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机译:具有嵌合包膜蛋白的病毒载体,所述嵌合包膜蛋白包含蛋白a的igg结合结构域
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摘要
The invention involves viral vectors that can be used to transduce a target cell, i.e., to introduce genetic material into the cell. The targets of interest are eukaryotic cells and particularly human cells. The transduction can be done in vivo or in vitro. More particularly the invention concerns viral vectors that have chimeric envelope proteins and contain the IgG-binding domain of protein A. These vectors when used in conjunction with antibodies targeting a particular cell are particularly useful for gene therapy.
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