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NEW BETAMIMETICS HAVING A LONG-LASTING ACTIVITY, PROCESSES FOR PREPARINGTHEM AND THEIR USE AS MEDICAMENTS

机译:具有长效活性的新药物学,制备方法及其作为药物的用途

摘要

The invention relates to betamimetics of the general formula (1), wherein R1represents a group (a), where R3 represents benzyl which can optionally besubstituted by methoxy, R4 represents hydrogen, or R3 and R4 conjointlyrepresent a -CO-CH2-O- bridge, whereby the carbonyl group of this bridge isbonded to the nitrogen; R2 represents a group selected from (b) and (c),whereby R5 represents dimethylamino, methoxy or butoxy, X represents anitrogen or a carbon, R6 represents methoxyphenyl if X is nitrogen, or if X iscarbon, an annellated phenyl ring likewise linked to X. The invention alsorelates to a method for the production of said betamimetics and to their useas medicaments.
机译:本发明涉及通式(1)的β模拟物,其中R 1代表基团(a),其中R 3代表苄基,其可以任选地为被甲氧基取代,R4代表氢,或R3和R4结合代表-CO-CH2-O-桥,其中该桥的羰基为与氮键合; R2代表选自(b)和(c)的基团,其中R5代表二甲基氨基,甲氧基或丁氧基,X代表氮或碳,如果X为氮或X为氮,则R6代表甲氧基苯基碳原子,同样与X连接的环化苯环。涉及所述β-模拟物的生产方法及其用途作为药物。

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