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Betamimetics having a long-lasting activity, processes for preparing them, and their use as medicaments
Betamimetics having a long-lasting activity, processes for preparing them, and their use as medicaments
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机译:具有持久活性的贝他米类似物,其制备方法及其作为药物的用途
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摘要
A compound of formula 1chemistry chemdraw filechemistry mol file;wherein R3 is a benzyl group optionally substituted by a methoxy group; R4 is a hydrogen atom, or R3 and R4 together are a COCH2O bridge, the carbonyl group of the bridge being bound to the nitrogen; and ;R2 is a group selected from chemistry chemdraw filechemistry mol file;wherein ;R5 is a dimethylamino, methoxy, or butoxy group, ;X is a nitrogen or a carbon atom, and ;R6 is a methoxyphenyl group, if X is nitrogen, or is an anellated phenyl ring also linked to X, if X is carbon, ;or the individual optical isomers, mixtures of the individual enantiomers, racemates, or acid addition salt thereof.
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机译:式 1 B> <化学id =“ CHEM-US-00001”> <图像文件=“ US20020022625A1-20020221-C00001.GIF”的化合物he =“ 135.37125” imgContent =“ undefined” imgFormat =“ GIF“ wi =” 212.65335“ /> 化学chemdraw文件 ExternalFileRef> 化学摩尔文件 ExternalFileRef> Chemistry>;其中R 3 Sup>是可被甲氧基取代的苄基; R 4 Sup>是氢原子,或R 3 Sup>和R 4 Sup>一起是COCH 2 Sub> O桥,桥的羰基与氮结合;和; R 2 Sup>是选自以下的组 <图像文件=“ US20020022625A1-20020221-C00002.GIF” he =“ 58.5711” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 156.74715” /> 化学chemdraw文件 ExternalFileRef> 化学摩尔文件< / ExternalFileRef> Chemistry>;其中; R 5 Sup>是二甲氨基,甲氧基或丁氧基;; X是氮或碳原子;; R 6 Sup>如果X为氮,则为甲氧基苯基;如果X为碳,为X,也为与X连接的带芳基的苯环;或各个旋光异构体,各个对映异构体的混合物,外消旋体或它们的酸加成盐。
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