A novel polypeptide, human plasminogen activator inhibitor 2-9 and the polynucleotide encoding thereof

摘要

The invention discloses a novel polypeptide, human plasminogen activator inhibitor 2-9, the polynucleotide encoding such polypeptide and the method of production thereof by DNA recombinant techniques. Methods of using the polypeptide for treating various diseases such as hemorrhagic disease, thrombosis, cerebral infarction, myocardial infarction, various tumors, inflammation, inflammation restoration abnormity related disease, hemopathy, developmental disorder, HIV infection and the like are also disclosed. Furthermore, the invention discloses the antagonists of the polypeptide and the effects thereof. The use of the polynucleotide encoding the novel human plasminogen activator inhibitor 2-9 is also disclosed.