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A NOVEL PACKAGING CELL LINE FOR THE RESCUE, PRODUCTION AND TITRATION OF HIGH-CAPACITY ADENOVIRUS AMPLICON VECTORS
A NOVEL PACKAGING CELL LINE FOR THE RESCUE, PRODUCTION AND TITRATION OF HIGH-CAPACITY ADENOVIRUS AMPLICON VECTORS
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机译:用于大容量腺病毒扩增子载体的拯救,生产和滴定的新型包装细胞系
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摘要
The present invention describes a method of producing adenovirus gutless amplicon viral vector substantially reduced in the content of helper virus. The invention also describes a system for the helper virus independent replication and packaging of adenovirus gutless vectors. A cell line for this system is also discussed.
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