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A NOVEL BACULOVIRUS/ADENOVIRUS HYBRID VECTOR FOR THE RESCUE, PRODUCTION AND TITRATION OF HIGH-CAPACITY ADENOVIRUS AMPLICON VECTORS
A NOVEL BACULOVIRUS/ADENOVIRUS HYBRID VECTOR FOR THE RESCUE, PRODUCTION AND TITRATION OF HIGH-CAPACITY ADENOVIRUS AMPLICON VECTORS
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机译:新型杆状病毒/腺病毒混合载体,用于大容量腺病毒扩增子的拯救,生产和滴定
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摘要
The present invention describes a recombinant baculovirus hybrid helper virus that is comprised of baculovirus sequences and second viral structural and late viral sequences. The invention also describes a method of producing gutless viral vectors that are substantially free from helper virus contamination. Furthermore, the invention describes a recombinant baculovirus BAC-B4 (VSVG).
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