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TROXERUTINE WITH HIGH TRIHYDROXY-ETHYL-RUTOSIDE CONTENT, HIGH WETABILITY, AND PREPARATION METHOD

机译:高三羟乙基芸苔苷含量,高可溶性的曲妥汀及其制备方法

摘要

The invention concerns novel troxerutin with high trihydroxy-ethyl-rutin content. Said troxerutin has at least 92 wt. % of 7,3',4'-trihydroxyethyl rutin and a wettability expressed in minutes less than 10 minutes, when said wettability is measured in a test consisting in measuring the time taken by 3.5 g of said enriched troxerutin powder to leave the surface of a beaker containing 100 ml of water, at a stabilised temperature of 20° C., when said enriched troxerutin powder is poured at the surface of the water in said beaker, and a wettability less than 100 seconds when said wettability is measured in a test consisting in measuring the time taken by said enriched troxerutin to be wetted by the water contained in a receptacle, such as a beaker, when said enriched troxerutin has been deposited at the surface of the water, in the form of cores of 2 mm wide and 3 mm high weighing 63 ? 2 mg, at a stabilised temperature of 20° C. Said troxerutin has improved properties of wettability and solubility in water.
机译:本发明涉及具有高三羟基乙基芦丁含量的新型曲格鲁汀。所述曲格鲁汀具有至少92重量%。 %的7,3′,4′-三羟乙基芦丁和以不到10分钟的分钟数表示的润湿性,是在测试中测量所述润湿性时进行的,该测试包括测量3.5g所述富集的troxerutin粉末离开表面的时间。当将所述富集的曲霉菌素粉末倒入所述烧杯中的水表面时,在20℃的稳定温度下,盛有100ml水的烧杯,并且在测试中测量所述湿润性时,其湿润性小于100秒包括测量当所述富集的troxerutin以2mm宽的芯的形式沉积在水表面时,所述富集的troxerutin被容纳在诸如烧杯之类的容器中的水润湿所花费的时间。 3毫米高重63?在20℃的稳定温度下为2mg。所述曲克芦丁具有改善的润湿性和在水中的溶解性。

著录项

  • 公开/公告号FR2787111B1

    专利类型

  • 公开/公告日2001-02-23

    原文格式PDF

  • 申请/专利权人 LABORATOIRES NEGMA;

    申请/专利号FR19980015710

  • 发明设计人 ESTANOVE CYRIL;PRUVOST FRANCOIS;

    申请日1998-12-11

  • 分类号C07H17/07;A61K31/7048;A61P9/14;

  • 国家 FR

  • 入库时间 2022-08-22 01:08:02

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