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Methods of screening for or treating cancers or autoimmune disorders in which a complement C3 or C3 related protein is associated
Methods of screening for or treating cancers or autoimmune disorders in which a complement C3 or C3 related protein is associated
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机译:筛选或治疗与补体C3或C3相关蛋白相关的癌症或自身免疫性疾病的方法
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摘要
Methods of screening for cancers or treating cancers or autoimmune disorders are disclosed. In an aspect of the present invention, the screening methods are based on the detection of complement C3 or C3 related protein, or a nucleic acid molecule encoding the same, found to be associated with the presence of cancer. Additional screening methods are based on the use of complement regulators Factor I or DAF, or complement receptors 1 or 3. Preferred embodiments to the methods include detection based on immunological properties, physical properties, enzymatic properties and combinations thereof, or detection of a nucleic acid molecule encoding antigen based on nucleic acid amplification.
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