composition, method, risk reduction method, prevention or treatment of an individual having an autoimmune disease or disorder, method of inducing degradation of a target protein in a cell, method for reducing risk, preventing or treating a disease state or disorder in a patient wherein the unregulated protein activity is responsible for said disease or condition, method for reducing the risk, preventing or treating cancer in an individual, and method of treating a genetic disease or disorder in an individual

摘要

These are small molecules against cereblon to enhance effector t-cell function. Methods of producing these molecules and methods of using them to treat various disease states are also disclosed.