Drug dependent treatment using opiate antagonists and serotonin compounds

摘要

Patients are treated for alcohol, marijuana, cocaine, opiate and polysubstance dependency by administration of combination of an effective amount of an opioid antagonist such as nalmefene, naloxone, naltrexone, or a mixture of any of these, and a serotonergic medication, such as sertraline, fluoxetine, paroxetine, fluvoxamine, or odansetron. Administration of an effective amount of an opioid antagonist alone helps to prevent relapse after detoxification is complete, and addition of the serotonergic medication increases the effectiveness, decreases the side effects of the opioid antagonist, and also helps relieve effects of withdrawal.