N- the method of producing the salt of asuparutemu from asuparutemu which is protected

摘要

(57) Abstract With the processing by acid the protective group the fact that it is disconnected is included, the ground pal chill phenylalanine methyl ester which first, N- is protected first N- in the method of producing the salt of ground pal chill phenylalanine methyl ester from the ground pal chill phenylalanine methyl ester which is protected, in water medium and under existing of methanol, at temperature of 0 - the 80C, of 0.8 - 2 equivalent asesuruhuamin acids and at least transformation to the salt of ground pal chill phenylalanine methyl ester and asesuruhuamin acid is sufficient and, the salt which the kind of time which is completed, it reacts, next, forms with first processAt temperature below the 30C, the method of featuring that you obtain in the form which settles.