首页> 外国专利> Composition for the treatment or prophylaxis of diseases treatable or preventable by enhancing the effect of a neurotrophin and a neurodegenerative disease, and uses of a 6 (5h) phenanthridinone derivative, and a compound

Composition for the treatment or prophylaxis of diseases treatable or preventable by enhancing the effect of a neurotrophin and a neurodegenerative disease, and uses of a 6 (5h) phenanthridinone derivative, and a compound

机译:通过增强神经营养蛋白和神经退行性疾病的作用来治疗或预防可治疗或可预防疾病的组合物,以及6(5h)菲啶酮衍生物和化合物的用途

摘要

"COMPOSITION FOR THE TREATMENT OR PROPHYLAXIS, OF TREATABLE OR AVOIDABLE DISEASES BY THE POTENTIALIZATION OF THE EFFECT OF A NEUROTROPHINE AND OF A NEURODEGENERATIVE DISEASE, AND USES OF A 6 (5H) FENANTRIDINE E DERIVATIVE,". Neurotrophin enhancers that contain 6 (5H) -phenanthridinone derivatives of the general formula (I) or pharmacologically acceptable salts thereof and are useful as preventive or therapeutic drugs for neurodegenerative diseases: in which, R ^ 1 ^ R ^ 1 '^, R ^ 2 ^ and R ^ 2 '^ are each, independently hydrogen or halogen; and either R ^ 3 ^ and R ^ 3 '^ is amino and the other hydrogen, with the proviso that when either R ^ 1 ^ and R ^ 1' ^ is halogen, the other is hydrogen and that when either R ^ 2 ^ and R ^ 2 '^ is halogen, the other is hydrogen.
机译:“通过强化神经营养和神经退行性疾病的治疗和预防性疾病或可预防性疾病的组成,以及使用6(5H)芬那定E衍生物。”含有6(5H)通式(I)的菲啶酮衍生物或其药理学上可接受的盐并可用作神经退行性疾病的预防或治疗药物的神经营养蛋白增强剂:其中,R ^ 1 ^ R ^ 1'^,R ^ 2 ^和R ^ 2'^分别独立地是氢或卤素; R ^ 3 ^和R ^ 3'^中的一个是氨基,另一个是氢,但前提是当R ^ 1 ^和R ^ 1'^是卤素时,另一个是氢,而当R ^ 2 ^并且R ^ 2'^是卤素,另一个是氢。

著录项

  • 公开/公告号BR0009846A

    专利类型

  • 公开/公告日2002-02-13

    原文格式PDF

  • 申请/专利权人 SANKYO COMPANY LIMITED;

    申请/专利号BR20000009846

  • 发明设计人 FUJIO ISONO;MIYUKI FUJII;ATSUSHI AOYAGI;

    申请日2000-04-19

  • 分类号C07D221/12;A61K31/473;A61P25/28;A61P25/16;A61P25/14;A61P25/02;

  • 国家 BR

  • 入库时间 2022-08-22 00:46:13

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