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Retroviral vector particles produced in a baculovirus expression system capable of delivering a nucleotide sequence of interest (NOI)
Retroviral vector particles produced in a baculovirus expression system capable of delivering a nucleotide sequence of interest (NOI)
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机译:在杆状病毒表达系统中产生的逆转录病毒载体颗粒能够传递目标核苷酸序列(NOI)
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摘要
A composition comprising at least one baculoviral vector and at least one polynucleotides sequence encoding a retroviral vector genome; wherein the polynucleotides sequence encoding the retroviral vector genome is operably linked to a promoter in the baculoviral vector. The promoter in the baculoviral vector comprises an RNA transcription start site for the retroviral vector genome; such that the polynucleotides sequence encoding the retroviral vector genome is capable of being transcribed and packaged into an infectious retroviral particle.
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