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USE OF IL-12 AND IL-12 ANTAGONISTS FOR THE PRODUCTION OF A MEDICINAL PRODUCT FOR THE TREATMENT OF AUTOIMMUNE DISEASES
USE OF IL-12 AND IL-12 ANTAGONISTS FOR THE PRODUCTION OF A MEDICINAL PRODUCT FOR THE TREATMENT OF AUTOIMMUNE DISEASES
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机译:IL-12和IL-12拮抗剂在生产用于治疗自身免疫性疾病的医药产品中的用途
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摘要
Method of treating autoimmune conditions are disclosed comprising administering to a mammalian subject IL-12 or an IL-12 antagonist. In certain preferred embodiments the autoimmune condition is one which is promoted by an increase in levels of IFN- gamma or TNF- alpha . Suitable conditions for treatment include multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, autoimmune pulmonary inflammation, Guillain-Barre syndrome, autoimmune thyroiditis, insulin dependent diabetes melitis and autoimmune inflammatory eye disease.
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