USE OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) INHIBITORS FOR REDUCING THE NUMBER OF POSTPRANDIAL TRIGLYCERIDE-RICH LIPOPROTEIN PARTICLES (PPTRL)

摘要

The invention relates to the use of inhibitors of the microsomal triglyceridetransfer protein (MTP) for reducing the number of postprandial triglyceride-rich lipoprotein particles (ppTRL) or for reducing their decompositionproducts i.e. the cholesterol-rich "small remnant particle" (remnants). Saidparticles are associated with apolipoprotein B-48 (ApoB-48) and are designatedas "ppTRL" in the further course of events.