Tgfbeta rii receptor nucleic sequence, coded peptide, and uses
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机译:Tgfbeta rii受体核酸序列,编码的肽和用途
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摘要
The invention concerns a peptide comprising or consisting of a first peptide sequence of not more than 20 consecutive amino acids defined in a second peptide sequence coded by all or part of SEQ ID NO: 42 and different from SEQ ID NO: 1, said peptide being capable of being fixed on at least a class I major histocompatibility complex (MHC I) glycoprotein. The invention also concerns all nucleic sequence coding for such a peptide and the uses thereof in a vector, a host cell and in a pharmaceutical composition for diagnosing, preventing or treating in particular gastric or colon cancers.
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机译:本发明涉及一种肽,其包含由以下组成的肽或由其组成的第一肽序列,该第一肽序列在由SEQ ID NO:42的全部或部分编码且不同于SEQ ID NO:1的第二肽序列中定义的不超过20个连续氨基酸。能够固定在至少I类主要组织相容性复合物(MHC I)糖蛋白上。本发明还涉及编码该肽的所有核酸序列及其在载体,宿主细胞和药物组合物中用于诊断,预防或治疗特别是胃癌或结肠癌的用途。
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