Processes for preparation of Marek's disease virus using continuous mammalian cell lines

摘要

The present invention relates to the use of continuous mammalian cell lines for the production of non-recombinant and recombinant Marek's Disease Virus, the production of genetically engineered Marek's Disease Virus and Marek's Disease Virus vectors, continuous mammalian cell lines infected with Marek's Disease Virus, Marek's Disease Virus vaccines produced using Marek's Disease Virus obtained using such processes and methods for protecting animals, such as avians, against disease by Marek's Disease Virus and/or other pathogens. Particularly, the mammalian cell lines capable of infection or transfection with MDV are feline kidney cell lines.