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NOVEL NATRIURETIC PEPTIDE RECEPTORS, INTERACTING COMPOUNDS AND METHODS OF REGULATING PROLIFERATION AND/OR SURVIVAL OF NEURONS
NOVEL NATRIURETIC PEPTIDE RECEPTORS, INTERACTING COMPOUNDS AND METHODS OF REGULATING PROLIFERATION AND/OR SURVIVAL OF NEURONS
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机译:新型利钠肽受体,相互作用化合物和调节神经元增殖和/或存活的方法
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摘要
The present invention provides methods and compositions for regulating proliferation and/or survival of neurons, to treat neuronal death and/or injury, or cancer, and to diagnose neuronal tumors, using compounds such as natriuretic peptides or PHI-related neuropeptides to interact with peptide receptor subtypes on the neurons, and provides a novel receptor on neurons that inhibits proliferation in response to natriuretic and PHI-related neuropeptides, and a novel natriuretic type-C receptor.
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