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REMEDIES OR PREVENTIVES FOR DIGESTIVE DISEASES CONTAINING DIAMINOTRIFLUOROMETHYLPYRIDINE DERIVATIVES

机译:含有二氨基三氟甲基乙炔吡啶衍生物的消化系统疾病的补救措施或预防措施

摘要

A digestive system disease therapeutic or preventive agent containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a -CW1R1 group, a -COCOR2 group, a -CW1NHCOR2 group, a -C(=W1)W2R3 group or a -CW1N(R4)R5 group; Y is an alkyl group, a -CW3R6 group, a -COCOR7 group, a -NHCOR7 group, a -C(=W3)W4R8 group, a -(NH)mSO2R9 group, a -(NH)mSO2OR10 group or a -(NH)mSO2N(R11)R12 group; each of R1, R6 and R9 is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R2 and R7 is an alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R3, R8 and R10 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R4, R5, R11 and R12 is an alkyl group; each of W1, W2, W3 and W4 is an oxygen atom or a sulfur atom; and m is 0 or 1.
机译:消化系统疾病的治疗或预防剂,含有式(I)表示的二氨基三氟甲基吡啶衍生物或其盐作为活性成分: <图像文件=“ IMGA0001.GIF” he =“ 35” imgContent =“ chem” imgFormat =“ GIF” wi =“ 88” /> 其中X是-CW < Sup> 1 R 1 组,-COCOR 2 组,-CW 1 NHCOR 2 组,则-C(= W 1 )W 2 R 3 组或-CW 1 N (R 4 )R 5 组; Y是烷基,-CW 3 R 6 基,-COCOR 7 基,-NHCOR 7 组,-C(= W 3 )W 4 R 8 组,-(NH) m SO 2 R 9 组,一个-(NH) m SO 2 OR 10 < / Sup>组或-(NH) m SO 2 N(R 11 )R 12 组; R 1 ,R 6 和R 9 分别为链状烃基,单环烃基,多环烃基,单环杂环基团或多环杂环基团; R 2 和R 7 分别为烷基,烷氧基,苯基或苯氧基。 R 3 ,R 8 和R 10 分别为烷基,烯基,炔基,环烷基,苯基基团或苄基; R 4 ,R 5 ,R 11 和R 12 分别为烷基。 W 1 ,W 2 ,W 3 和W 4 分别是氧原子或硫原子。 m为0或1。

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