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REGULATOR OF CELLULAR GROWTH IN VITRO AND METHOD FOR CELLULAR GROWTH REGULATION IN VITRO

机译:体外细胞生长调节剂和体外细胞生长调节方法

摘要

FIELD: medicine, pathophysiology, clinical oncohematology. SUBSTANCE: the method applies electrostimulant of gastro- intestinal tract designed as a medicinal capsule. The capsule's electrodes represent isolated parts of the mentioned one. Both an impulse generator and a supply unit are placed inside the capsule. The latter is put into cellular suspension to conduct electric impact upon cells in vitro. To obtain positive regulation of cellular growth in vitro an impact is carried out for about 5-60 min, not less. To obtain negative regulation of cellular growth in vitro - for about 180 min, not less. An impact is performed with impulse current at 5- 7 msec impulse duration, 9-16 mA current power and about 4.5 V tension amplitude between electrodes, not more. EFFECT: improved conditions to conduct electric impact upon cells being simultaneous, steady and approximate to physiological one, simplified conditions to obtain both positive and negative regulation of cellular growth in vitro, enhanced convenience of application. 3 cl, 4 tbl
机译:领域:医学,病理生理学,临床肿瘤血液学。物质:该方法适用于设计为药用胶囊的胃肠道电刺激剂。胶囊的电极代表所述电极的隔离部分。脉冲发生器和供应单元都放置在胶囊内部。后者被置于细胞悬液中以在体外对细胞进行电冲击。为了获得体外细胞生长的正调节,进行约5-60分钟,不少于5分钟。为了获得体外细胞生长的负调控-持续约180分钟。冲击电流以5到7毫秒的脉冲持续时间,9-16毫安的电流功率以及电极之间大约4.5伏的张紧幅度(不多)来执行。效果:改善了对细胞进行电击的条件,使其同时,稳定且接近生理学条件;简化了条件,可在体外获得细胞生长的正向和负向调节;增强了应用的便利性。 3厘升,4汤匙

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