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Process for the identification of specifically cleavable peptides and use of such peptide sequences

机译:鉴定特异性可裂解肽的方法和此类肽序列的用途

摘要

The invention relates to methods for detecting and identifying peptides that can be specifically cleaved, using a defined amino acid sequence based on a library of nucleic acid peptide fusion molecules. According to said methods, the variable part of the peptides is coded by the respective nucleic acid fused thereto, using proteolytically active solutions. The invention also relates to the use of said peptides for the targeted release of chemical active ingredients and for diagnosis.
机译:本发明涉及使用基于核酸肽融合分子文库的确定的氨基酸序列,检测和鉴定可以特异性切割的肽的方法。根据所述方法,使用蛋白水解活性溶液,通过与之融合的相应核酸编码肽的可变部分。本发明还涉及所述肽在化学活性成分的靶向释放和诊断中的用途。

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