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cephalosporins in position 7 substituiertes benzyloxyiminoradikal contain, method of manufacture and interconnection to their production, their use as medicines

机译:位置7的取代基头孢亚苄基亚基放射性头孢菌素所含的头孢菌素,其生产方法及其与生产的相互关系,用作药物的用途

摘要

Syn isomer of cpds. of formula (I), and their salts, are new. In (I), R1-R3, R5 = H, halo, OH, 1-4C alkyl (opt. substd. by halo, 1-4C alkyloxy, SH etc.); R4 = OH or 1-8C acyloxy; R7 = H or (1-3C alkyloxy)carbonyl; A = e.g. H, an equivalent of alkali(ne earth) metal, Mg, ammonium or aminated organic base etc.; or CO2A = CO2-; wavy line shows that CH2R6 can be in E- or Z-position; R6 = e.g. quat. ammonium or gp. of formula (i); X = CH2, NH, O or S; and Y, T, U, V, W and Z = CH or N; with the provisos.
机译:cpds的同分异构体。式(I)的化合物及其盐是新的。在(I)中,R 1 -R 3,R 5 = H,卤素,OH,1-4C烷基(优选被卤素,1-4C烷氧基,SH等取代); R4 = OH或1-8C酰氧基; R7 = H或(1-3C烷氧基)羰基; A =例如H,相当于碱(土)金属,Mg,铵或胺化有机碱等;或CO2A = CO2-;或波浪线表示CH2R6可以位于E或Z位置; R6 =例如qua铵或gp。式(i); X = CH2,NH,O或S; Y,T,U,V,W和Z = CH或N;附带条件。

著录项

  • 公开/公告号DE69616702D1

    专利类型

  • 公开/公告日2001-12-13

    原文格式PDF

  • 申请/专利权人 AVENTIS PHARMA S.A. ANTONY;

    申请/专利号DE19966016702T

  • 申请日1996-08-13

  • 分类号C07D501/24;C07C59/64;C07C69/734;C07D209/48;C07D277/20;C07C239/20;A61K31/545;

  • 国家 DE

  • 入库时间 2022-08-22 00:25:21

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