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steroidderivate, a substituiertes thioethylradikal part 10 of the steroids, methods for their production and intermediates thereof, their use as medicines and pharmaceutical preparations thereof

机译:类固醇衍生物,类固醇的取代基硫乙基基10部分,其生产方法及其中间体,其作为药物的用途及其药物制剂

摘要

Products of formula (I): …IMAGE… in which:… R = H, alkyl, alkenyl, alkynyl, haloalkyl or alkylthio, (- 6c) or arylthio, aryl, acyl (- 12c) or CN (CH2)m-Rc in which Rc denotes OH, SH or Salk (1 to 6c), cycloalk (3 to 6c), m = 1, 2 or 3, X = O N-OR1, R1 = H, alk or …IMAGE… (- 10c), Z = H; alk (- 10c), n = 0, 1 or 2, the dotted lines denote the optional presence of a second bond, process for their preparation and the intermediates of this process, their application as medications and the pharmaceutical compositions containing them.
机译:式(I)的产物:... ...其中:... R = H,烷基,烯基,炔基,卤代烷基或烷硫基(-> 6c)或芳硫基,芳基,酰基(-> 12c)或CN(CH2 )m-Rc,其中Rc表示OH,SH或Salk(1至6c),环烷基(3至6c),m = 1,2或3,X = O N-OR1,R1 = H,alk或... …(-> 10c),Z = H; alk(-> 10c),n = 0、1或2,虚线表示第二键的可选存在,其制备过程和该过程的中间体,其作为药物的用途以及包含它们的药物组合物。

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