Steroid products carrying a substituted thioethyl group in position 10, a process for their preparation and intermediates of this process, their use as medicines and pharmaceutical preparations containing them

摘要

Products of formula (I): …IMAGE… in which:… R = H, alkyl, alkenyl, alkynyl, haloalkyl or alkylthio, (- 6c) or arylthio, aryl, acyl (- 12c) or CN (CH2)m-Rc in which Rc denotes OH, SH or Salk (1 to 6c), cycloalk (3 to 6c), m = 1, 2 or 3, X = O N-OR1, R1 = H, alk or …IMAGE… (- 10c), Z = H; alk (- 10c), n = 0, 1 or 2, the dotted lines denote the optional presence of a second bond, process for their preparation and the intermediates of this process, their application as medications and the pharmaceutical compositions containing them.