For extrinsic gene introduction to the windpipe epithelium cell it rearranges, the Sendai virus vector

摘要

(57) Abstract For extrinsic gene introduction to the windpipe epithelium cell it rearranges and it offers the extrinsic gene introduction manner which uses the Sendai virus vector and its vector. Brief just makes the rearrangement Sendai virus vector, the windpipe epithelium cell of the non treatment contact which is covered with the mucus it is possible to introduce the gene efficiently. Furthermore, not only the Tip surface of the cell, CFTR to introduce the gene into also the systematic gland under the mucous membrane which it has revealed mainly it is possible this vector. Therefore, as for this vector CFTR using for the gene remedy for CF which is the disease which deficiency has been done is possible.