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Fab' epitopu complex of HIV1 intersection neutralization monoclonal antibody 2F5

机译:HIV1相交中和单克隆抗体2F5的Fab'表位复合体

摘要

(57) Abstract Laboratory stocks and the complex of the peptide array ELDKWAS to which, envelope protein gp41 of the virus of Fab'huragumento of Mab 2F5 which is the counteragent which is greatly both of the first clinical isolate of many cognate subpopulations of HIV1 effective is retained extensively was formed, and non compound both crystalline structure was elucidated, property of peptide - protein interaction was decided. Pertaining to this decision, control can do the peptide imitation body, to kind of three-dimensional structure which grants the antigenicity which the epitopu array confronts and increases.
机译:(57)<摘要>实验室库存和肽阵列ELDKWAS的复合物,与之相对应的是Mab 2F5 Fab'huragumento病毒的包膜蛋白gp41,它是对反义药,在很大程度上,它是许多同种亚群的第一个临床分离株形成有效保留的HIV1,并阐明了非化合物的两个晶体结构,决定了肽-蛋白质相互作用的性质。根据这一决定,控制可以使肽模仿体成为一种三维结构,赋予表位阵列所面对和增加的抗原性。

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