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Use of specific antibody titers to predict hepatic failure in people infected with hepatitis C virus

机译:使用特异性抗体滴度预测丙型肝炎病毒感染者的肝衰竭

摘要

A method is provided for determining the risk of hepatic failure in an individual who is infected with the hepatitis C virus (HCV). The method comprises measuring a titer of an antibody to the HCV core in a body fluid of the individual and correlating the titer to the risk of developing hepatic failure wherein the titer is inversely related to that risk. The method employs standard techniques for measuring the titer including solution and solid phase immunoassays. Kits incorporating the reagents and instructions for carrying out the methods are also provided.
机译:提供了一种方法,用于确定感染了丙型肝炎病毒(HCV)的个体的肝衰竭风险。该方法包括测量个体的体液中针对HCV核心的抗体的效价,并将该效价与发生肝衰竭的风险相关联,其中该效价与该风险成反比。该方法采用标准技术来测定滴度,包括溶液和固相免疫测定。还提供了包含试剂的试剂盒和执行该方法的说明。

著录项

  • 公开/公告号US2003032031A1

    专利类型

  • 公开/公告日2003-02-13

    原文格式PDF

  • 申请/专利权人 GOEDERT JAMES J.;TODD JOHN A.;

    申请/专利号US20020098857

  • 发明设计人 JAMES J. GOEDERT;JOHN A. TODD;

    申请日2002-03-13

  • 分类号C12Q1/70;C12Q1/68;G01N33/53;A61K39/29;

  • 国家 US

  • 入库时间 2022-08-22 00:11:02

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