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Transgenic cells and a method for detecting disruptors for androgens by using said transgenic cells

机译:转基因细胞和使用所述转基因细胞检测雄激素破坏者的方法

摘要

A transgenic cell is disclosed, where includes a culture cell, and an androgen receptor-expression vector and a foreign reporter gene introduced into said culture cell, said foreign reporter gene having a gene promoter, which is a target of said androgen and an androgen receptor, inserted therein. This transgenic cell is used for detecting a disrupter in a material to be examined through examining the expression of the foreign reporter gene when being brought into contact with the material.
机译:公开了一种转基因细胞,其包括培养细胞,雄激素受体表达载体和引入所述培养细胞的外源报道基因,所述外源报道基因具有基因启动子,所述基因启动子是所述雄激素和雄激素受体的靶标,插入其中。该转基因细胞用于通过检查与材料接触时外源报道基因的表达来检测待检查材料中的破坏物。

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