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HUMANIZED IMMUNOGLOBULIN REACTIVE WITH B7-2 AND METHODS OF TREATMENT THEREWITH

机译：人源化免疫球蛋白与B7-2的反应及其治疗方法

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摘要

The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.

机译：本发明涉及人源化抗B7-2抗体，其包含非人类来源的可变区和人类来源的免疫球蛋白的至少一部分。本发明还涉及通过施用人源化抗B7-2和/或抗B7-1抗体来治疗各种自身免疫疾病，移植排斥，炎性疾病和感染性疾病的方法。

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公开/公告号US2002176855A1

专利类型
公开/公告日2002-11-28

原文格式PDF
申请/专利权人 CO MAN SUNG;VASQUEZ MAXIMILIANO;CARRENO BEATRIZ;CELNIKER ABBIE CHERYL;COLLINS MARY;GOLDMAN SAMUEL;GRAY GARY S.;KNIGHT ANDREA;OHARA DENISE;RUP BONITA;VELDMAN GEERTRUIDA M.;
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申请/专利号US19990249011
发明设计人 MAN SUNG CO;MAXIMILIANO VASQUEZ;BEATRIZ CARRENO;ABBIE CHERYL CELNIKER;MARY COLLINS;SAMUEL GOLDMAN;GARY S. GRAY;ANDREA KNIGHT;DENISE OHARA;BONITA RUP;GEERTRUIDA M. VELDMAN;
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申请日1999-02-12
分类号C07H21/02;A61K39/40;C07H21/04;C12P21/04;A61K39/395;A61K39/42;C12N15/09;C12N1/20;C12N15/00;C12N15/63;C12N15/70;C12N15/74;C12N5/16;C12N5/06;C12N15/85;C12N5/00;C12N5/12;C12P21/08;C07K16/00;C12N15/87;
国家 US
入库时间 2022-08-22 00:09:16

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