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Dialysis solution including polyglycol osmotic agent

机译:包含聚乙二醇渗透剂的透析液

摘要

Dialysis solutions comprising aqueous solutions including physiologically acceptable salts and a polyglycol osmotic agent are disclosed. The subject solutions provide an improved osmotic gradient resulting in reduced dialysis times and/or reduced volumes of required dialysis solution. Moreover, the subject osmotic agents do not significantly migrate into the patient's blood over the time period of dialysis nor are the subject osmotic agents as susceptible to forming detrimental degradation products during gamma sterilization. The use of free radical scavengers is also described along with the use of a filter to reduce the introduction of bacteria into the peritoneal cavity.
机译:公开了包含水溶液的透析溶液,所述水溶液包含生理学上可接受的盐和聚乙二醇渗透剂。本发明的溶液提供了改善的渗透梯度,从而减少了透析时间和/或减少了所需透析液的体积。此外,本发明的渗透剂在透析期间不会显着迁移到患者的血液中,本发明的渗透剂也不易在伽马灭菌过程中形成有害的降解产物。还描述了自由基清除剂的使用以及过滤器的使用,以减少细菌向腹膜腔的引入。

著录项

  • 公开/公告号US2003202958A1

    专利类型

  • 公开/公告日2003-10-30

    原文格式PDF

  • 申请/专利权人 STRICKLAND ALAN D.;SIMON JAIME;

    申请/专利号US20030396671

  • 发明设计人 ALAN D. STRICKLAND;JAIME SIMON;

    申请日2003-03-25

  • 分类号A61K31/765;A61K38/05;A61K31/198;A61K31/375;A61K31/555;B01D11/00;

  • 国家 US

  • 入库时间 2022-08-22 00:08:25

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