A pirimidinonas substituted Compound, Pharmaceutical composition containing same and use of said compound and the composition in the manufacture of Drugs useful for Selective inhibition of the coagulation Cascade

摘要

Pirimidinona substituted Compound of formula (1) or a Salt acceptable for pharmaceutical use of the sameWhere the substituents are as described in the specification and claims; it includes Pharmaceutical Composition and the use of these compounds and compositions in the manufacture of Drugs useful as inhibitors of Serine proteases of the coagulation Cascade and The Prevention and Treatment of various conditions which include the ARTERI thrombotic DiseasesA coronary and cerebrovascular diseases.