MICROBIAL PRODUCTION OF VITAMIN B12 AND PRODUCTION AND USE OF COMPOSITIONS CONTAINING VITAMIN B12 IN HIGH CONCENTRATIONS

摘要

The present invention provides a process for the preparation of natural vitamin B12, wherein said process comprises the steps of: a) culturius microbial cells so that they produce, intracellularly, natural vitamin B12, b) causing opening of the microbial cells such that vitamin B12 is released. The present invention concerns also a composition comprising natural vitamin B12 in an amount greater than 0,1% weight based on the dry matter content of the composition.