PHENYLETHANOLAMINE COMPOUNDS, USEFUL AS BETA3 AGONISTS, PROCEDURE FOR YOUR PRODUCTION AND INTERMEDIATES OF YOUR PRODUCTION.

摘要

THIS INVENTION REFERS TO PHENYLETHANOLAMINE COMPOUNDS REPRESENTED THROUGH THE GENERAL FORMULA [I]: (WHERE R 1 REPRESENTS HYDROGEN OR HALOGEN; R 2 REPRESENTS HYDROGEN, HYDROXYL, LOWER ALCOXY, OXYXIOXY BIOXYXIOXYBIOXYXIOBY BIOXYXIOBIOXYPROXYBIOXIOXYPYROXYBIOBROXYBY BIOXYXIOBIOXYPE substituted lower alkylaminocarbonyl lower one, which may be substituted by lower alkoxy, lower alkoxy substituted by aminocarbonyl CICLICO 4 TO 6 carbon atoms, alkoxycarbonyl or carboxy LOWER; R 3 represents hydrogen, hydroxyl, lower alkoxy or lower alkoxy substituted by OR TWO LOWER ALCOXICARBONYL OR CARBOXI GROUPS; R 2 AND R3 CAN BE UNITED BETWEEN TO FORM MEETENDENDXI REPLACED BY CARBOXY OR LOWER ALCOXICARBONYL; YMYN ARE 0 OR 1). ALSO, THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS ARE INCLUDED, WHICH PRESENT A POWERFUL BE 3 AD RENERGIC STIMULATING EFFECT AND A HIGH SELECTIVITY FOR THE BE 3 ADRENERGIC RECEIVER, AS WELL AS PROCESSES FOR THEIR PRODUCTION AND INTERMEDIARIES FOR SUCH PRODUCTION.