Use of a superoxide dismutase mimetic catalyst in the manufacture of a medicament for preventing and treating hiv-mediated central nervous system damage

摘要

The present invention relates to methods of preventing and/or treating HIV-mediated central nervous system damage. The method comprises administering to a subject therapeutic amounts of non-proteinaceous catalysts for the dismutation of superoxide to a subject either alone or in combination with a HIV anti-viral agent. The compounds of the invention are particularly suitable for treating and/or preventing AIDS Dementia Complex.