Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo

摘要

Methods and compositions for recruiting cells circulating in the blood stream of a subject to a blood contacting surface, and in particular, devices and methods for recruiting endothelial cells to a blood contacting surface of a prosthesis as well as engineering a self-endothelializing graft in vivo by recruitment of circulating endothelial progenitor cells (EPCs) to form a neo-endothelium on a prosthetic structure.